AMT Overview

Experienced and dedicated team

Led by Dr. Sebastian Marcuccio

AMT is a specialist chemical company focused on the development and commercialisation of new Intellectual Property and products, including oranoboron, organosilicon and bioactive nucleoside analogues. Our expert and dedicated chemistry team offers a personalised service taking care to meet your needs. AMT is involved, but not limited to, the following services:

 Traditional synthesis of complex molecules

 Structure-Based Drug Design

 Synthesis of scaffolds, building blocks & lead optimisation

 Synthesis of metabolites, impurities & reference compounds

 Route design & synthesis for new target molecules

 Synthesis of pharmacologically active reference compounds or positive controls

 Synthetic intermediates & specialty custom organic reagents

 Synthesis of small focused libraries

 Analoging of core skeleton

 Organometallic chemistry: Suzuki, Hiyama, Sonogashira, Heck, Buckwald, Mg, Zn reactions etc.

 Deuterated and 13C labelled compounds

 Privileged structure search

 Knowledge mining for IP score optimisation

 Rational design, bioisosteric replacement

 Custom manufacture of items where a source is undefined

 Sourcing special fine chemicals and organic intermediates

For more information, please email us at: enquiries@amtechpl.com

Keywords: organoboron, phenylboronic acid, boronic acid, boronic acid ester, diboron, trifluoroborate, organosilicon, nucleoside, nucleotide, prodrug, catalyst, halide, diaryl, biaryl, Hiyama, Suzuki-coupling, Kumada, Stille, cross-coupling, HOMSi, silane, palladium, stannane, tributyltin, medicinal chemistry, active pharmaceutical ingredients, intellectual property, building block, custom synthesis, contract research.